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1

G-Protein Coupled Receptors Virtual Screening Using Genetic Algorithm Focused Chemical Space

Sage, Carleton, Wang, Runtong, Jones, Gareth

Journal:

Journal of Chemical Information and Modeling

Year:

2011

Language:

english

File:

PDF, 4.29 MB

english, 2011

2

The Manuscripts of St. Aelred

Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1949

Language:

english

File:

PDF, 814 KB

english, 1949

3

The Monastic Order in England: A History of Its Development from the Times of St. Dunstan to the Fourth Lateran Council 943-1216by David Knowles

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1941

Language:

english

File:

PDF, 470 KB

english, 1941

4

β-Tubulin mutation suppresses microtubule dynamics in vitro and slows mitosis in vivo

Dr. Carleton R. Sage, Dr. Ashley S. Davis, Cynthia A. Dougherty, Kevin Sullivan, Kevin W. Farrell

Journal:

Year:

1995

Language:

english

File:

PDF, 1.51 MB

english, 1995

5

3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b

Philip J. Skinner, Martin C. Cherrier, Peter J. Webb, Carleton R. Sage, Huong T. Dang, Cameron C. Pride, Ruoping Chen, Susan Y. Tamura, Jeremy G. Richman, Daniel T. Connolly, Graeme Semple

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 129 KB

english, 2007

6

5-N,N-Disubstituted 5-aminopyrazole-3-carboxylic acids are highly potent agonists of GPR109b

Philip J. Skinner, Peter J. Webb, Carleton R Sage, Huong T. Dang, Cameron C. Pride, Ruoping Chen, Susan Y. Tamura, Jeremy G. Richman, Daniel T. Connolly, Graeme Semple

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 193 KB

english, 2009

7

Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a)

P. Douglas Boatman, Thomas O. Schrader, Michelle Kasem, Benjamin R. Johnson, Philip J. Skinner, Jae-Kyu Jung, Jerry Xu, Martin C. Cherrier, Peter J. Webb, Graeme Semple, Carleton R. Sage, Jens Knudsen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 651 KB

english, 2010

8

Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control

Graeme Semple, Albert Ren, Beatriz Fioravanti, Guillherme Pereira, Imelda Calderon, Karoline Choi, Yifeng Xiong, Young-Jun Shin, Tawfik Gharbaoui, Carleton R. Sage, Michael Morgan, Charles Xing, Zhi-L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

9

1-Alkyl-benzotriazole-5-carboxylic Acids Are Highly Selective Agonists of the Human Orphan G-Protein-Coupled Receptor GPR109b

Semple, Graeme, Skinner, Philip J., Cherrier, Martin C., Webb, Peter J., Sage, Carleton R., Tamura, Susan Y., Chen, Ruoping, Richman, Jeremy G., Connolly, Daniel T.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 131 KB

english, 2006

10

Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists

Daniel Buzard, Sangdon Han, Lars Thoresen, Jeanne Moody, Luis Lopez, Andrew Kawasaki, Thomas Schrader, Carleton Sage, Yinghong Gao, Jeff Edwards, Jeremy Barden, Jayant Thatte, Lixia Fu, Michelle Solom

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

11

Discovery of a second generation agonist of the orphan G-protein coupled receptor GPR119 with an improved profile

Graeme Semple, Juerg Lehmann, Amy Wong, Albert Ren, Marc Bruce, Young-Jun Shin, Carleton R. Sage, Michael Morgan, Wei-Chao Chen, Kristen Sebring, Zhi-Liang Chu, James N. Leonard, Hussein Al-Shamma, An

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 347 KB

english, 2012

12

The additivity of substrate fragments in enzyme–ligand binding

Thomas J Stout, Carleton R Sage, Robert M Stroud

Journal:

Year:

1998

Language:

english

File:

PDF, 504 KB

english, 1998

13

GPCRs: an update on structural approaches to drug discovery

Nigel R.A. Beeley, Carleton Sage

Journal:

Year:

2003

Language:

english

File:

PDF, 405 KB

english, 2003

14

Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer

Christopher L. Reyes, Carleton R. Sage, Earl E. Rutenber, Robert M. Nissen, Janet S. Finer-Moore, Robert M. Stroud

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 2.11 MB

english, 1998

15

3-(1 H -Tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): A Partial Agonist of the Nicotinic Acid Receptor, G-Protein Coupled Receptor 109a, with Antilipolytic but No Vasodilatory Activity in Mice

Semple, Graeme, Skinner, Philip J., Gharbaoui, Tawfik, Shin, Young-Jun, Jung, Jae-Kyu, Cherrier, Martin C., Webb, Peter J., Tamura, Susan Y., Boatman, P. Douglas, Sage, Carleton R., Schrader, Thomas O

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 184 KB

english, 2008

16

Analogues of Acifran: Agonists of the High and Low Affinity Niacin Receptors, GPR109a and GPR109b

Jung, Jae-Kyu, Johnson, Benjamin R., Duong, Tracy, Decaire, Marc, Uy, Jane, Gharbaoui, Tawfik, Boatman, P. Douglas, Sage, Carleton R., Chen, Ruoping, Richman, Jeremy G., Connolly, Daniel T., Semple, G

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 48 KB

english, 2007

17

Molecular Hashkeys: A Novel Method for Molecular Characterization and Its Application for Predicting Important Pharmaceutical Properties of Molecules

Ghuloum, Anwar M., Sage, Carleton R., Jain, Ajay N.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 151 KB

english, 1999

18

Mutation in the β-Tubulin Signature Motif Suppresses Microtubule GTPase Activity and Dynamics, and Slows Mitosis †

Dougherty, Cynthia A., Sage, Carleton R., Davis, Ashley, Farrell, Kevin W.

Journal:

Year:

2001

Language:

english

File:

PDF, 91 KB

english, 2001

19

Elucidating Molecular Overlays from Pairwise Alignments Using a Genetic Algorithm

Jones, Gareth, Gao, Yinghong, Sage, Carleton R.

Journal:

Journal of Chemical Information and Modeling

Year:

2009

Language:

english

File:

PDF, 4.07 MB

english, 2009

20

Site-Directed Mutagenesis of Putative GTP-Binding Sites of Yeast .beta.-Tubulin: Evidence That .alpha.-, .beta.-, and .gamma.-Tubulins Are Atypical GTPases

Sage, Carleton R., Dougherty, Cynthia A., Davis, Ashley S., Burns, Roy G., Wilson, Leslie, Farrell, Kevin W.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.86 MB

english, 1995

21

An Essential Role for Water in an Enzyme Reaction Mechanism: The Crystal Structure of the Thymidylate Synthase Mutant E58Q †,‡

Sage, Carleton R., Rutenber, Earl E., Stout, Thomas J., Stroud, Robert M.

Journal:

Year:

1996

Language:

english

File:

PDF, 599 KB

english, 1996

22

D221 in Thymidylate Synthase Controls Conformation Change, and Thereby Opening of the Imidazolidine †,‡

Sage, Carleton R., Michelitsch, Melissa D., Stout, Thomas J., Biermann, Donna, Nissen, Robert, Finer-Moore, Janet, Stroud, Robert M.

Journal:

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

23

Purification and biochemical characterization of tubulin from the budding yeast Saccharomyces cerevisiae

Davis, Ashley, Sage, Carleton R., Wilson, Leslie, Farrell, Kevin W.

Journal:

Year:

1993

Language:

english

File:

PDF, 2.56 MB

english, 1993

24

L'Ordre Cistercien et son Gouvernement des Origines au Milieu du XIII^e Siecle (1098-1265)

Sage, Carleton M., Mahn, Jean Berthold

Journal:

The American Historical Review

Year:

1947

Language:

english

File:

PDF, 144 KB

english, 1947

25

Investigating interactions between phentermine, dexfenfluramine, and 5-HT2Cagonists, on food intake in the rat

Grottick, Andrew J., Whelan, Kevin, Sanabria, Erin K., Behan, Dominic P., Morgan, Michael, Sage, Carleton

Journal:

Psychopharmacology

Year:

2015

Language:

english

File:

PDF, 663 KB

english, 2015

26

Intronic U14 snoRNAs of Xenopus laevis are located in two different parent genes and can be processed from their introns during early oogenesis

Xia, Ling, Liu, Joyce, Sage, Carleton, Trexler, E.Brady, Andrews, Matthew T., Maxwell, E.Stuart

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 4.02 MB

english, 1995

27

Epistolario de Alvaro de Cordobaby José Madoz

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1948

Language:

english

File:

PDF, 300 KB

english, 1948

28

The English Clergy and Their Organization in the Later Middle Agesby A. Hamilton Thompson

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1948

Language:

english

File:

PDF, 424 KB

english, 1948

29

Cistercian Settlements in Wales and Monmouthshire, 1140–1540. (Fordham University Studies, History Series No. 2.)by Jeremiah F. O'Sullivan

Review by: Carleton M. Sage

Journal:

Year:

1947

Language:

english

File:

PDF, 371 KB

english, 1947

30

Richard of Cornwallby N. Denholm-Young

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1948

Language:

english

File:

PDF, 311 KB

english, 1948

31

Church Life in England in the Thirteenth Centuryby J. R. H. Moorman

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1946

Language:

english

File:

PDF, 454 KB

english, 1946

32

Two Lives of St. Cuthbertby Bertram Colgrave

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1941

Language:

english

File:

PDF, 330 KB

english, 1941

33

The English Austin Friars in the Time of Wyclifby Aubrey Gwynn

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1941

Language:

english

File:

PDF, 208 KB

english, 1941

34

Canterbury Cathedral Priory. A Study in Monastic Administrationby R. A. L. Smith

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1945

Language:

english

File:

PDF, 496 KB

english, 1945

35

The Religious Orders in Englandby David Knowles

Review by: Carleton M. Sage

Journal:

The Catholic Historical Review

Year:

1949

Language:

english

File:

PDF, 437 KB

english, 1949

36

Discovery of 2-(((1 r ,4 r )-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension

Tran, Thuy-Anh, Kramer, Bryan, Shin, Young-Jun, Vallar, Pureza, Boatman, P. Douglas, Zou, Ning, Sage, Carleton R., Gharbaoui, Tawfik, Krishnan, Ashwin, Pal, Biman, Shakya, Sagar R., Garrido Montalban,

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 680 KB

english, 2017

37

Cistercian Settlements in Wales and Monmouthshire, 1140–1540. By Jeremiah F. O'Sullivan (Fordham University Studies, History Series No. 2.) New York, Declan X. McMullen Co., 1947. Pp. ix, 137.

Sage, Carleton M.

Journal:

Year:

1947

File:

PDF, 680 KB

1947

38

Cistercian Settlements in Wales and Monmouthshire, 1140–1540. By Jeremiah F. O'Sullivan (Fordham University Studies, History Series No. 2.) New York, Declan X. McMullen Co., 1947. Pp. ix, 137.

Carleton M. Sage, S.S.

Journal:

Year:

1947

Language:

english

File:

PDF, 680 KB

english, 1947

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